Simons Haplomics

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Dr. Carol Nottenburg

Patent Analysis

Curriculum Vitae of Dr Simons

Dr Simons' Patents

Dr Simons' historical (Junk DNA) non-coding Patents were assigned to GeneType AG in the late 1980's and early 1990's.

The following Patent information is from the Genetic Technologies web site:

Genetic Technologies Limited

Genetic Technologies' patents covering 'non-coding' DNA form two families:

1.  Intron Sequence Analysis

This patent family describes a method whereby information can be extracted from the non-coding sequences associated with genes.  These sequences include introns, promoters and untranslated regions. This information can be used in several commercial contexts.  It is based on the realisation that much of the non-coding region is not ‘junk’ (as it was believed to be for many years) but is in fact highly correlated with the coding region and frequently has functional consequences for the human, animal or plant host.  This invention enables the interrogation of the non-coding regions in DNA to draw conclusions about the associated coding region.

This invention arose initially from studies in the 1980’s of the human HLA complex on chromosome six, and was then demonstrated to be applicable to gene sequences in plants and animals as well. As a result, broad and powerful patents have been granted to GTG in Australia, the USA, Europe and many other countries

2.  Genomic Mapping

This patent family covers the now widely accepted method of gene discovery and mapping involving the use of non-coding polymorphisms (variations in the non-coding region) as markers for locating the gene of interest on a particular chromosome. This technology, currently used mainly by gene researchers, is also now starting to be employed in the context of disease diagnostics.

Dr Simons' other Genetic Technologies' patents include:

Fetal Cell Separation- RareCellect®
This patented invention concerns the identification, separation and collection of live fetal cells from the blood of a pregnant woman.  This process will permit routine chromosomal and DNA testing on the foetus, avoiding the invasive procedures of amniocentesis or chorionic villus biopsy. Two broad patents have been issued and the science is under development.

HLA Locus Specific Primers
This invention supports human haplotyping investigations with sequences that are useful for the development of diagnostic kits.

Internal Standards
This is a novel method developed by GTG to standardise a routine DNA testing procedure known as electrophoresis, to ensure better reading of DNA patterns. GTG's Internal Standards invention is patented in USA and elsewhere and has been licensed non-exclusively to Pharmacia Biotech (Sweden).

For current information regarding Dr. Simons, please visit:  http://www.SimonsHaplomics.com

For further reading material on Junk DNA, please visit:  http://www.junkdna.com

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This web site was last updated on 18th July 2004