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CURRICULUM VITAE
DR. MALCOLM J. SIMONS MB.ChB, MD (Otago,NZ), DMedSci (Tokyo,Japan), FACA, FRCPA
Date of Birth: 10 December, 1939.
Nationality: New Zealand.
DEGREES/FELLOWSHIPS:
MB.ChB. Bachelor of Medicine, Bachelor of Surgery University of Otago, Dunedin, New Zealand 1962
FRCPA Fellow, Royal College of Pathologists of Australasia 1974
FACA Fellow, Australian College of Allergy 1974
MD Doctor of Medicine (Distinction) University of Otago, Dunedin, New Zealand 1977
D.Med.Sci. Doctor of Medical Science University of Tokyo, Japan 1977
APPOINTMENTS/CONSULTANTSHIPS:
Past:
1. Director of Science, GeneType AG, CH‑6300 Zug, Switzerland 1989-2000
2. Consultant, Simons GeneType Diagnostics Pty Ltd Australia 1989-2000
3. Consultant, Genetic Technologies Ltd, Australia 2000-2003
Present:
1. Founder-Scientist Simons HAPLOMICS Ltd 2003-
Past:
1. Consultant Immunologist, Immunodiagnostic Centre, North Melbourne, Australia. 1968-87
2. Consultant Pathologist, Immunolabs Assays / Analytic Reference Labs, North Melbourne, Australia. 1968-87
3. Consultant Immunopathologist, Immunology (Pathology) Laboratories, Singapore. 1976-87
4. Associate, Department of Pathology and Immunology, Monash University, Prahran, Australia. 1978-87
5. Consultant Immunogeneticist, Immunogene Typing Laboratories, Immunosearch Pty. Ltd., North Melbourne, Australia. 1981-87
6. Consultant Immunogeneticist, Division of Laboratory Medicine, Royal Southern Memorial Hospital, Caulfield, Australia. 1985-89
7. Consultant in Biotechnology, CP Ventures Ltd., Melbourne, Australia. 1985-86
8. Past President/Councillor, 3rd Asia‑Oceania Histocompatibility Workshop Conference, Sapporo, Japan. 1985-86
9. President, 2nd Asia‑Oceania Histocompatibility Workshop Conference, Melbourne, Australia. 1980-81
10. Principal Investigator, Anti‑Cancer Council of Victoria. Immunogenetics & Immunovirology Programme on Cervical Cancer. Prince Henry's Hospital, Melbourne, Australia. 1977-80
11. Scientist and Head, World Health Organisation Immunology Research and Training Centre for the Western Pacific and Southeast Asian regions, National University of Singapore, Singapore. 1970-76
12. Principal Investigator, International Agency for Research on Cancer, Lyon, France / National Cancer Institute, National Institute of Health, U.S.A. Cancer Research Programme, National University of Singapore, Singapore. 1970-76
13. Consultant Immunologist, Division of Serology and Immunology, Institute for Medical Research, Kuala Lumpur, Malaysia. 1974-76
14. WHO Technical Advisory Committee on Dengue Haemorrhagic Fever, Bangkok, Thailand. 1975
15. WHO/University of North Sumatra/Ministry of Health Population Health Survey in Samosir & Nias Islands, North Sumatra, Indonesia. 1974-75
16. WHO Working Group on the Organisation of Comprehensive Cancer Control Programmes in the Western Pacific Region, Manila, Philippines. 1975
17. WHO International Agency for Research on Cancer, Postgraduate Course in Immunovirology of Cancer, Lyon, France. 1974
18. WHO/Indian Council for Medical Research 3rd Annual Immunology Training Course, New Delhi, India. 1974
19. WHO‑Assisted Workshop on Hepatitis B antigen, Tokyo, Japan. 1973
20. WHO Scientific Group on Viral Hepatitis, Geneva, Switzerland. 1972
21. WHO Immunology Workshop for the Southeast Asian Region, Bangkok, Thailand. 1972
22. Singapore Ministry of Health Expert Committee on Australia (Hepatitis B) Antigen Singapore 1971-76
23. Senior Research Fellow, National Health and Medical Research Council, Royal Children's Hospital Research Foundation, Parkville, Australia. 1967-70
24. Research Fellow, National Health and Medical Research Council, Royal Children's Hospital Research Foundation, Parkville, Australia. 1964-67
LEARNED SOCIETIES:
American Society for Histocompatibility and Immunogenetics Australasian and Southeast Asian Tissue Typing Association Australian Society of Immunology and Allergy Inc Australian Medical Association Australian Society for Clinical Ecology Australian Society of Immunology Inc Clinical Immunology Group of Australia Human Genetics Society of Australasia International Epidemiology Association International Society for Haematology International Society for Oncological Biology and Medicine International Union for the Scientific Study of Populations Malaysian Society for Parasitology and Tropical Medicine New York Academy of Sciences Royal Society for Tropical Medicine and Hygiene Royal Society of Medicine Singapore Medical Association Singapore Society for Immunology Society for the Study of Human Biology Transplantation Society of Australia and New Zealand Victorian Society of Pathology and Experimental Medicine
PUBLICATIONS (excluding Abstracts):
1. Simons, M.J. (1962). The effect of massive antigenic stimulation on blood vessels of the rat's brain. Proc. Univ. Otago Med. School, 40, 27.
2. Heslop, B.F. and Simons, M.J. (1962). The concept of Auto‑immunity. N.Z. Med. J., 61, 174.
3. Simons, M.J. (1963). Self‑recognition as a biological mechanism. In: Hemlock, Bull. Cant. Univ. (NZ) Socratic Society (ed. Lorking, D.), 4, 26.
4. Simons, M.J. (1964). Research and teaching in biology. In: Hemlock, Bull. Cant. Univ. (NZ) Socratic Society (ed. Lorking, D.), 5, 16.
5. Simons, M.J. and Fowler,R. (1966). Chorioallantoic membrane lesions produced by inoculation of adult fowl small lymphocytes. Nature, 209, 588.
6. Simons, M.J. (1966). Experimental renal transplantation. Proc. XIth Congr. Int. Soc. Blood Transfusion, pp. 273‑281.
7. Simons, M.J., Schumacher, M.J. and Fowler, R. (1968). Intravenous gammaglobulin therapy of immunoglobulin deficiency diseases. Aust. Paed. J., 4, 127.
8. Simons, M.J., Fowler, R. and Fitzgerald, M.G. (1968). Mechanism of small lymphocyte reactivity induced by PHA in culture: The role of PHA determinants and lymphocyte membrane reactive sites. Nature, 219, 1021.
9. Simons, M.J. (1968). Anti‑lymphocyte serum. Lancet, 1, 866.
10. Simons, M.J. and Fitzgerald, M.G. (1968). Rubella virus and human lymphocytes in culture. Lancet, 2, 937.
11. Simons, M.J. and Jack, I. (1968). Lymphocyte viraemia in congenital rubella. Lancet, 2, 953.
12. Simons, M.J. (1968). Congenital rubella: An immunological paradox? Lancet, 2, 1275.
13. Simons, M.J. (1968). Project ANZ‑ASIA. In: The generation gap and Australian‑Asian relations (ed. Jordens, J.T.F.) Australian‑Asian Association of Victoria, pp. 88‑104.
14. Schumacher, M.J., Dreher, G.H. and Simons, M.J. (1968). Thymic hypoplasia and immunoglobulin synthesis. Aust. Paed. J., 4, 252.
15. Simons, M.J. and Fitzgerald, M.G. (1969). Apparent dissociation of antigen responsiveness and antibody production by small lymphocytes in culture. Clin. exp. Immunol., 4, 55.
16. Simons, M.J., Fowler, R. and Fitzgerald, M.G. (1969). The reactivity of human small lymphocytes in culture: the effect of concentration and duration of exposure to phytohaemagglutinin. Cell. Tiss. Kinet., 2, 1.
17. Simons, M.J. (1970). How to use an Immunology laboratory. Med. J. Aust., 2, 643.
18. Simons, M.J. (1970). Trends in immunoglobulin therapy. Med. J. Aust., 2, 683.
19. Simons, M.J., Hosking, C.S. and Hogarth‑Scott, R.D. (1970). The current status of IgE in allergic reactions. Australasian Ann. Med., 19, 366.
20. Simons, M.J. (1970). ANZ‑ASIA: A human biological view. In: Everyman in Australia. The Octagon lectures (ed. Bolton,G.C.), Univ. Western Australia Press, pp. 54‑66.
21. Blake, N.M., Kirk, R.L., Simons, M.J. and Alpers, M.P. (1970). Genetic variants of soluble malate dehydrogenase in New Guinea populations. Humangenetik, 11, 72.
22. Simons, M.J., Fitzgerald, M.G. and Alpers, M.P. (1971). Lymphocyte function in Kuru. In: Proc. 6th. Congr. Neuropath., Masson, Paris. pp. 825‑826.
23. Simons, M.J., Yap, E.H., Yu, M., Seah, C.S., Chew, B.K., Fung, W.P., Tan, A.Y.O. and Shanmugaratnam, K. (1971). Frequency of Australia antigen in Singapore Chinese patients with hepatocellular carcinoma. Lancet, 1, 1149.
24. Simons, M.J., Ong, Y.W. and Yap, E.H. (1971). Australia antigen in Singapore. III. Significance as a public health problem. In: Proc. 6th Singapore‑Malaysia Congr. Med. (ed. Chew, C.H.), pp. 213‑218.
25. Simons, M.J. (1971). Project ANZ‑ASIA: Further proposals for human population studies. Search (J. Aust. NZ. Assoc. for the Advancement of Science). 2, 369‑376.
26. Fung, W.P., Ong, Y.W., Kwa, S.B., Tan, K.K., Yap, E.H. and Simons. M.J. (1971). Anicteric viral hepatitis in blood donors. Med. J. Aust., 2, 888.
27. Hogarth‑Scott, R.S., Howlett, B.J., McNicol, K.N., Simons, M.J. and Williams, H.E. (1971). IgE levels in the sera of asthmatic children. Clin. exp. Immunol., 9, 467.
28. Hosking, C.S., Fitzgerald, M.G. and Simons, M.J. (1971). Quantified deficiency of lymphocyte response to phytohaemagglutinin in immune deficiency diseases. Clin. exp. Immunol., .
29. Morris, P.J., Ting, A., Alpers, M.P. and Simons, M.J. (1971). Leucocyte antigens in a New Guinea population. Tissue Antigens, 1, 49‑52.
30. Ong, Y.W., Kwa, S.B., Ying, C.S., Yap, E.H. and Simons, M.J. (1971). Australia antigen in Singapore. I. Frequency in blood donors. Singapore Med. J., 12, 189.
31. Ting, A., Wee, G.B., Simons, M.J. and Morris, P.J. (1971). The distribution of HLA leucocyte antigens in Singapore Chinese, Malays and Indians. Tissue Antigens, 1, 258‑264.
32. Yap, E.H., Ee, T.I. and Simons, M.J. (1971). Detection of Australia antigen by electro‑osmodiffusion (EOD). Southeast Asian J. of Trop. Med. Public Health, 2, No. 4, 486.
33. Simons, M.J. (1972). Some recent advances in Immunology ‑or ‑ Immunology goes human: approaches to patient and population Immunology. In: Proc. 7th Malaysia‑Singapore Medical Congr., Kuala Lumpur, (eds. Kutty, K., Ng, K. F. and Mohanadas, A.). pp. 209‑213.
34. Simons, M.J., Binns, C.W., Malcolm, L.A. and Yap, E.H. (1972). Australia antigen in two groups of highland New Guineans. Papua New Guinea Med. J., 15, 91.
35. Simons, M.J. (1972). Australia antigen in hepatocellular carcinoma. Lancet, 2, 1089‑1090.
36. Simons, M.J., Yap, E.H., Yu, M. and Shanmugaratnam, K. (1972). Australia antigen in Singapore Chinese patients with hepatocellular carcinoma and comparison groups: Influence of technique sensitivity on differential frequencies. Int. J. Cancer, 10, 320‑325.
37. Simons, M.J., Yap, E.H., Ong, Y.W., Okochi, K., Mayumi, M. and Nishioka, K. (1972). Frequency of Australia antigen in blood donors in Singapore. Amer. J. Dis. Child.,123, 405.
38. Simons, M.J., Yap, E.H., Yu, M., Seah, C.S., Chew, B.K., Fung, W.P., Tan, A.Y.O. and Shanmugaratnam, K. (1972). Frequency of Australia antigen in Chinese patients in Singapore with hepatocellular carcinoma. Amer. J. Dis. Child., 123, 358.
39. Curtain, C.C. and Simons, M.J. (1972). Tissue binding antibodies in tropical populations. Trans. Roy. Soc. Trop. Med., 66, 292.
40. Curtain, C.C. and Simons, M.J. (1972). Lymphocyte mitogens of indigenous Australian plant species. Int. Arch. Appl. Immunol., 42, 225.
41. Yap, E.H., Ong, Y.W., Simons, M.J., Okochi, K., Mayumi, M. and Nishioka, K. (1972). Australia antigen in Singapore. II. Differential frequency in Chinese, Malays and Indians. Vox. Sang., 22, 371.
42. Zaman, V., Ascheim, L., Yap, E.H. and Simons, M.J. (1972). Detection of malarial antibodies by countercurrent immunoelectrophoresis. Sing. Med. J., 13, 305‑306.
43. Simons, M.J., Kwa, S.B., Day, N.E., Wee, G.B., Hawkins, B.R., de The, G.B. and Shanmugaratnam, K. (1973). Immunogenetic studies of Southeast Asian ethnic groups with high and low risk for NPC. In: Analytic and Experimental Epidemiology of Cancer. Proc. 3rd Int. Cancer Symposium of the Princess Takamatsu Cancer Research Fund (eds. Nakahara, W., Hirayama, T., Nishioka, K. and Sugano, H. ). Univ. of Tokyo Press, Tokyo, pp. 171-193.
44. Simons, M.J., Detection of AFP by radioelectro-complexing (1973). Tumour Research, 8, 37.
45. Simons, M.J., Yu, M. and Shanmugaratnam, K. HB Antigenaemia, specific immune deficiency and hepatocellular carcinoma (1973). Tumour Research, 8, 121.
46. Beng, C.G., Chan, G.L., Simons, M.J. and Lau, K.S. (1973). Semi‑quantitation of serum IgE by counterimmunoelectrophoresis. Int. Arch. All. Appl. Immunol., 45, 352‑359.
47. Blake, N.M., McDermid, E.M., Kirk, R.L., Ong, Y.W. and Simons, M.J. (1973). The distribution of red cell enzyme groups among Chinese and Malays in Singapore. Sing. Med. J., 14, 2‑8. |